David Mayes Middleton II (born September 18, 1981) is an American businessman and politician serving as a member of the Texas Senate for the 11th district.

[7] Middleton owns and manages ranching, cattle, and farming operations in Chambers, Jefferson, Kimble, Liberty, and Webb Counties.

[3] In the 2018 primary election, he successfully challenged two-term incumbent representative Wayne Faircloth, an ally of House Speaker Joe Straus.

[27][28] He serves on the board of directors of the Wallisville Heritage Park, a historical museum in Chambers County, Texas.

[29][30] Middleton is a former member of the board of directors of the Texas Public Policy Foundation (TPPF).

He was elected to the board in January 2016, but had to relinquish his seat in June 2017 when he announced his candidacy for the Texas House of Representatives due to a requirement in the foundation's bylaws.