He played college football for the Michigan Wolverines, winning three consecutive Big Ten Conference titles and a national championship in 2023.

He was raised by his father and older brother Kevin Jr.[2] Edwards' grandfather Charlie Primas Jr. won Mr. Basketball of Michigan in 1950.

[13] On December 31, in the Fiesta Bowl (CFP semifinal), Edwards rushed for his third straight 100-yard game with 119 yards on 23 carries in the loss to TCU.

[14] In 2023, Edwards played in all 15 games on Michigan's national championship team, finishing with 746 rushing and receiving yards, five touchdowns and a career-high 30 receptions.

He became the first player in college football history, since the BCS launched in 1998, to have two rushing touchdowns of over 40 yards in a national championship game, and led Michigan to victory versus the Washington Huskies.

[17] Entering his senior season, Edwards was ranked as one of the top running backs in college football by members of the media.

[21][22] Edwards assumed the role as the leader for the Wolverines in 2024 and was voted as team captain, filling both the starting running back and leadership position held by his predecessor Blake Corum.