[4] Lahela "Doogie" Kameāloha is a child prodigy juggling her teenage life and family with an early medical career, as well as having to deal with balancing her relationship with her mother, who is also her boss.

The website's critics consensus reads, "With a winning cast and a great bedside manner, Doogie Kamealoha, M.D.

[20] Daniel Fienberg of The Hollywood Reporter stated that the series serves as an example of how a franchise can be modernized across time, claiming it succeeds to provide a story that can appeal to the nostalgic audience of Doogie Howser, M.D.

[21] Joel Keller of Decider claimed that the show manages to distinguish itself from Doogie Howser, M.D by creating its own identity, citing its gender-flipped lead character and the story sets in Hawaii, found the series funny and family-oriented, and praised the chemistry between the actors and their performances.

[22] Caroline Framke of Variety described the show as a sweet, bright, and earnest Disney Channel sitcom.

[23] Polly Conway of Common Sense Media rated the series 4 out of 5 stars, acclaimed the depiction of positive messages, citing compassion, courage, and teamwork, applauded the presence of positive role models, stating that Peyton Elizabeth Lee's character demonstrates sensitivity and consideration for the needs of other individuals, while complimenting the diversity of the cast members.