[3] Papadimitriou made her television debut as an actress in the early 2000s in Mega Channel's daily series Forbidden Love, playing a small role.

Her first starring television role came in the 2003–2004 season in the NET comedy series Shedon Pote, directed by Nikos Perakis.

There she played Vanda Pappa, a young up-and-coming actress, co-starring with Anna-Maria Papacharalambous, Vana Rabota and Annita Koulis in the first cycle of the series.

Alongside Almost Never, from March to May 2004 he had a key role in the cast of the third cycle of Christoforos Papakaliatis's drama series Close Your Eyes.

On the one hand, she joined the lead cast of the second cycle of the daily series of Elena Akrita and Giorgos Kyritsis Vera sto Dexi on Mega Channel, having the role of Anna Damianou, while on the other hand she starred with Thanasis Efthimiadis in the comedy series of Alpha TV Confusions.

[10] There she played Angeliki Asteriou, a flight attendant who has an extramarital affair, co-starring with, among others, Elisavet Konstantinidou, Meleti Ilias, Traiana Anania and Konstantinos Aspiotis.

After the end of Dancing with the Stars, she took over the presentation of Skai's infotainment show Xtypa Xylos from September to December 2013, which was about children and the prevention of child accidents.

[16] In March 2015, she presented Mega Channel's game show Greece S'Agapo in the station's prime time zone.

[18] On 27 April 2016, shortly before the end of the show, she announced that "Kalimeroudia" was temporarily suspended due to the financial problems faced by the television station Mega Channel.

Papadimitriou's first well-known work in the ttheatretook place in the 2009–10 season, with the show The Black Box staged at the Jeni Karezi Theatre.

Her next appearance on the big screen was in 2007 in Nikolas Dimitropoulos' film "Alter ego" where she starred alongside Sakis Rouvas.