The Douglas, Arizona Port of Entry is a port of entry on the Mexico–United States border.

It connects Douglas, Arizona with Agua Prieta, Sonora.

It is near the southern terminus of U.S. Route 191 in Arizona and the northern terminus of Mexican Federal Highway 17, which connect the towns of Douglas and Agua Prieta to their respective national highway networks.

The current border inspection station was built in 1933, was significantly renovated and expanded by the General Services Administration in 1993, and was listed on the U.S. National Register of Historic Places in 2014.

In 2015, this facility was renamed the "Raul Hector Castro Port of Entry", after former Arizona Governor Raúl Héctor Castro.