The Downshire Hospital is a 16-bed psychiatric hospital at Downpatrick, County Down, Northern Ireland, for both psychiatric intensive-care patients and low secure rehabilitation.

The hospital, which was designed by Henry Smyth, was opened as the Down Lunatic Asylum in 1869.

[2] It became the Down Mental Hospital in the 1920s and joined the National Health Service as Downshire Hospital in 1948.

[2] Following the introduction of Care in the Community in the early 1980s, the hospital went into a period of decline and provision for patients reduced from over 300 beds to just 16.

[3] Part of the building was subsequently converted for use as offices for Down District Council who began operating there in October 2012.