The Dr. Herman S. Dreer House is a historic building built in 1930 and located at 4335 Cote Brilliante Avenue in The Ville neighborhood of St. Louis, Missouri.

[1] Dreer's children retained ownership of the building until 2000.

[1] It has been listed as one of the National Register of Historic Places since February 20, 2009 for African American ethnic heritage and education.

[1] As of 2012, the rest of the city block is part of the National Register-listed Marshall School Neighborhood in The Ville Historic District.

This article about a property in St. Louis, Missouri on the National Register of Historic Places is a stub.