[2] The atheistic Dr. Henry Jekyll (Lewis) embarks on a series of experiments determined to segregate the two sides of the human personality, good and evil, to disprove God's existence.

His experiments cause his fiancée Bernice to call off their engagement, and in a rage, he manages to unleash the darkest part of his personality as Mr. Hyde.

Hyde, complete with fangs and scraggy hair, skulks through the city, committing heinous acts.

[4] Reviewer Troy Howarth commented "The script allows the character (of Dr. Jekyll) more background detail....but Lewis fails to bring him to life.The makeup is low key; some false teeth, matted hair and a cocked hat.....his frantic overacting makes the character unintentionally humorous....it's hard to believe even audiences of the period would've found him credibly sinister.

[3] Sheldon Lewis returned once again in 1929 to play Dr. Jekyll in an early one-reel sound film short.