Drano (styled as Drāno) is an American brand of chemical drain cleaner that is manufactured by S. C. Johnson & Son.

Drano Aerosol Plunger was developed in the late 1960s, intended as a safer product that would be kinder environmentally.

In the late 1970s, the product was reformulated as a combination of liquid lye and sodium hypochlorite.

In 2017, a Drano bomb severely burned a 12-year old girl in the neighborhood of Harlem in New York City.

Drano bombs have the ability to cause third-degree burns and blindness.