At the beginning of 2010, a new modern depot facility for approximately 90,000 objects and works of art was completed.

[8] The museum conducted a CT scan and endoscopy of a statue of Buddha that documented the presence of a mummy identified as that of a monk, Liuquan, a Buddhist master of the Chinese Medical School.

The stolen artifacts included the 5th-century BCE Helmet of Coțofenești and Dacian bracelets.

[13] The museum has a large permanent collection of prehistoric artifacts from the province of Drenthe.

In the garden stands a statue of Bartje Bartels, the main character of books by Anne de Vries,[19] and a symbol of the province of Drenthe.

The museum holds a permanent collection of figurative art with particular attention to Realism from northern Europe and representatives of the fourth generation of Dutch abstract figurative artists such as Matthijs Röling.