Drishane Castle is a MacCarthy tower house and National Monument located in County Cork, Ireland.

Tadhg, son of Owen was in possession of Drishane Castle in 1592 when he surrendered it to Queen Elizabeth I and got a regrant.

All MacCarthy lands were forfeit after the Irish Confederate Wars (1641–53), but were restored to Donough MacCarty, 1st Earl of Clancarty in 1660 when Charles II regained the throne.

The land fell to the Hollow Sword Blade Company, who sold it to Henry Wallis in 1709; the Wallises took full ownership in 1728.

It became a convent in 1909, owned by the Sisters of the Infant Jesus, who operated a boarding secondary school for girls until 1992.