In the period of the temporary occupation of the town by Nazi Germany its riches were heavily plundered.

But already on the fourth day after the literation of the town by Soviet forces, on October 9, 1944, the museum resumed its activity.

[1] Among the materials of the exhibition there are archeological finds, articles of Drohobych artisans, implements of production and articles of peasants' everyday life; the museum presents numerous documents elucidating different periods in the country's history, printed books published in Ukraine before the 18th century, a collection of the 17th–19th century majolica, works of local and West European fine arts, etc.

While getting acquainted with St. George's and Holy Cross churches, remarkable monuments of wooden folk architecture of Galician school of the late 15th early 16th centuries, the visitor can view specimens of medieval icon-painting and unique wall paintings of the interiors carried out in Renaissance style.

[2] On display are Yuriy Drohobych's portrait by I. Marchuk, painter, a photocopy of his astronomic treatise, and xerocopy of his lecture schedule in the Bologna University.