It is one of the seven species groups in the subgenus Sophophora, the others being the D. willistoni, D. melanogaster, D. obscura, D. dispar, D. fima, and D. dentissima groups.
The D. saltans species group is most closely related to the D. willistoni subgroup.
It is thought that, like the D. willistoni species group, the D. saltans species group originated in tropical North America, colonized South America, and then diversified prior to the formation of the Isthmus of Panama.
Some of these may have migrated back to North America within the last 4.5 million years ago (mya), and consequently the relationship between the species is unresolved due to the short amount of time that has elapsed since their divergence points.
[1][2][3] This article related to members of the fly family Drosophilidae is a stub.