Dry Run is a tributary of the West Branch Susquehanna River in Northumberland County, Pennsylvania, in the United States.

[1] Dry Run joins the West Branch Susquehanna River 16.87 miles (27.15 km) upstream of its mouth.

[3] At the point where Dry Run crosses a Conrail railroad, the stream's peak annual discharge has a 10 percent chance of reaching 1,080 cubic feet per second (31 m3/s).

[4] At the point where Dry Run crosses Township Route 627, the stream's peak annual discharge has a 10 percent chance of reaching 960 cubic feet per second (27 m3/s).

[5] A concrete tee beam bridge carrying State Route 1005 over Dry Run was built 2 miles (3.2 km) north of Watsontown in 1948 and is 26.9 feet (8.2 m) long.

A concrete channel beam bridge carrying State Route 1003 over the stream was built in 1950 and repaired in 2009.

A prestressed box beam or girders bridge carrying Pennsylvania Route 44 across the stream was built 0.5 miles (0.80 km) north of Watsontown in 1962 and is 37.1 feet (11.3 m) long.

[8] In 2015, the Northumberland County Conservation District received a $200,000 Growing Greener grant to install animal fencing and implement streambank stabilization on Dry Run.