Duncan McIntyre (23 December 1834 – 13 June 1894) was a Scots-Quebecer businessman from Callander noted for his participation in the Canadian Pacific Railway syndicate of 1880 and as a founder of the Bell Telephone Company of Canada.

McIntyre's nephew, John Ferguson, staked out the future North Bay, Ontario after getting assurance from his uncle and Worthington that it would be the divisional point and a location of some importance.

The CPR started its westward expansion from Bonfield, Ontario (previously called Callander Station) where the first spike was driven into a sunken railway tie.

Bonfield, Ontario was inducted into Canadian Railway Hall of Fame in 2002 as the CPR First Spike location.

He married Jane Allan Cassils and they were the parents of four sons and three daughters, In the 1880s, McIntyre commissioned architect William Thomas to design a residence for him on a ten-acre plot within the Golden Square Mile.