ECU Health Duplin Hospital is a hospital located in Kenansville, North Carolina.

It is affiliated with the ECU Health Medical Center & ECU Health in Greenville, NC.

The hospital opened in 1955 and added a nine-bed intensive care unit in the 1970s.

The hospital added 55,000 square feet (5,100 m2) in 1989.

It has 20 general nursing home beds and three Shared Inpatient/Ambulatory Surgery operating rooms.