It was first described by the British ophthalmologist Henry Eales (1852–1913) in 1880[1] and is a rare ocular disease characterized by inflammation and possible blockage of retinal blood vessels, abnormal growth of new blood vessels (neovascularization), and recurrent retinal and vitreal hemorrhages.

[2] The disease is identified by its three characteristic steps: vasculitis, occlusion, and retinal neovascularization, leading to recurrent vitreous hemorrhages and vision loss.

Epiretinal membranes (ERM) can also be found on patients where the disease has progressed along to retinal detachment, Rubeosis iridis, neovascular glaucoma, cataracts, and optic atrophy.

[4] Symptoms of Eales disease include: mild reduction in vision due to vitreous hemorrhages, headaches, dyspepsia, constipation, and epistaxis.

Eye floaters may develop indicating the possibility of the progression of the disease to a point where retinal detachment is a concern.

[4] The only variation in the signs and symptoms seems to come from the varying severity of vasculitis and damage done to the eyes from vitreous hemorrhages causing different levels of vision deficiencies.

These tests include fundus fluorescein angiography (FFA) and ocular coherence tomography (OCT).

Differential diagnosis are as follows; retinopathy of prematurity (ROP) sequelae, familial exudative vitreoretinopathy, sarcoidosis, Behçet disease, sickle cell anemia, Terson syndrome, post traumatic vitreous hemorrhage, juvenile diabetes and primary branch retinal vein occlusion.

[7] •If active TB is present - treat with ATT •otherwise manage the vitreous hemorrhage - Partial h’ge - postural management with propped up position Total h’ge - Pars Plana Vitrectomy[6] Eales Disease most commonly affects healthy young adults.

The disease is now seen most commonly in the Indian subcontinent and its global incidence appears to be declining, probably largely due to improved public health and nutrition.