While certain Initial Upper Paleolithic populations represented by specimens found in Central Asia and Europe, such as the Ust'-Ishim man, Bacho Kiro or Oase 2, are inferred to have used inland routes, the ancestors of all modern East Eurasian populations are inferred to have used a Southern dispersal route through South Asia, where they subsequently diverged rapidly.
[16] This divergence most likely occurred in the Persian Plateau, correlating with the spread of Initial Upper Paleolithic material culture into Central Asia, Siberia, eastern Europe, and Northwestern China along a northern inland route.
[7][1][8]: 11 Traces of an unsampled deeply diverged East Eurasian lineage can be observed in the genome of ancient and modern inhabitants of the Tibetan Plateau.
While modern Tibetans mostly derive their ancestry from a northern East Asian source (specifically Yellow River farmers), a minor, but significant contribution stems from a deeply diverged East Eurasian local "Ghost population" that was distinct from other deeply diverged lineages such as Ust'Ishim, Hoabinhian/Onge or Tianyuan, representing the local Paleolithic population of the Tibetan Plateau.
[21][22] Deeper IUP-associated East Eurasian lineages have been associated with the remains of the Ust'-Ishim man from Siberia, and the Oase and Bacho Kiro cave specimens in southeastern Europe, and represent early inland migrations, deeply diverged from all other East Eurasian populations.