Except for two industrial park switching operations, all are former Pennsylvania Railroad or Reading Company lines, abandoned or sold by Conrail or its predecessors.

[citation needed] A yard was also constructed in Pocopson, Pennsylvania along the Wilmington and Northern Branch (W&N).

[2] ESPN attempted to abandon the Colebrookdale line between Pottstown and Boyertown in 2008; it was eventually purchased by Berks County.

In August 2022, six cars derailed in Chester County, narrowly missing a home.

[5] ESPN operates 114 miles of track in eastern Pennsylvania and northern Delaware and 16 commercial locomotives.

This line consists of owned trackage in the Manheim, Pennsylvania area, interchanging with NS.

The Octoraro line, which is owned and operated by ESPN, consists of trackage, the former Octoraro Branch, from end-of-track in Sylmar east to Chadds Ford, Pennsylvania, where it connects to the Wilmington and Northern Branch.