Ecdysteroid

[5] These compounds are synthesized in arthropods from dietary cholesterol upon metabolism by the Halloween family of cytochrome P450s.

Phytoecdysteroids also appear in many plants mostly as a protection agents (toxins or antifeedants) against herbivore insects.

[10] Ecdysterone has been tested on mammals due to the interest in its potential hypertrophic effect.

It has been found to increase hypertrophy in rats at a similar level to some anabolic androgenic steroids and SARMs.

[11] This is proposed to be through increase of Calcium leading to activation of Akt and protein synthesis in skeletal muscles.