[2] Echinopsis cuzcoensis grows tree-shaped with numerous, somewhat spreading branches and reaches heights of 5 to 6 meters.

About twelve very strong, stiff thorns emerge from them and are swollen at their base.

[3] Echinopsis cuzcoensis is widespread in the Cusco region of Peru at altitudes of 3100 to 3600 meters.

The first description by Nathaniel Lord Britton and Joseph Nelson Rose was published in 1920 as Trichocereus cuzcoensis.

[4] The specific epithet cuzcoensis refers to the occurrence of the species near the Peruvian city of Cusco.