Ectatomin is a protein toxin from the venom of the ant Ectatomma tuberculatum.

Ectatomin can efficiently insert into the plasma membrane, where it can form channels.

Ectatomin was shown to inhibit L-type calcium currents in isolated rat cardiac myocytes.

The structure of ectatomin reveals that each subunit consists of two alpha helices with a connecting hinge region, which form a hairpin structure that is stabilized by disulfide bridges.

A disulfide bridge between the hinge regions of the two subunits links the heterodimer together, forming a closed bundle of four alpha helices with a left-handed twist.