They live in a suburban cul-de-sac in the fictional town of Peach Creek along with fellow neighbourhood children Kevin, Nazz, Sarah, Jimmy, Rolf, Jonny, and the Eds' female adversaries, the Kanker Sisters, Lee, Marie and May.

Under the unofficial leadership of Eddy, the trio frequently invents schemes to make money from their peers to purchase their favourite confection, jawbreakers.

The show attracted an audience of 31 million households, was broadcast in 120 countries,[3] and proved to be popular among children, teenagers, and adults.

The group of kids are Jonny (David Paul "Buck" Grove), a loner whom his peers consider to be a nuisance, and spends most of his time with his imaginary friend, a wooden board named Plank; Jimmy (Keenan Christensen), a weak, insecure, and accident-prone child, who is most often seen spending his time with Sarah (Janyse Jaud), Ed's spoiled and ill-tempered younger sister who is attracted to Edd; Rolf (Peter Kelamis), an immigrant whose customs often differ from the other children's; Kevin (Kathleen Barr), a cynical and sardonic jock who detests the Eds, particularly Eddy; Nazz (Tabitha St. Germain; Jenn Forgie; Erin Fitzgerald), usually seen with Kevin, is a calm and friendly blonde girl who the Eds, Jonny, and Kevin are infatuated with.

During the fifth season, silhouettes of other people were occasionally shown, and in "Mission Ed-Possible", the arms of Eddy's father and Ed's mother were seen.

[6] In 1996, he faxed a one-page concept sheet and pitched the series to Nickelodeon,[6][7] but the network declined to give him creative control, and Antonucci refused.

[7] After an affirmative response from Cartoon Network president Betty Cohen, the legal paperwork and deal-making began, followed by a start-up meeting at the Chateau Marmont hotel in Los Angeles.

[8] Rolf is based on Antonucci and his cousins, since he was part of an Italian immigrant family, and grew up in a first-generation foreign household with different customs and ways of living, compared to those born in Canada.

[8] Some wanted Plank to be able to talk, smile and blink as if he was alive, but Antonucci insisted that it should be treated as a piece of wood, brought to life by Jonny's imagination.

David Paul "Buck" Grove and Keenan Christensen played the parts of Jonny 2×4 and Jimmy, respectively, while Sarah was voiced by Janyse Jaud.

[10] Antonucci, an advocate of hand-drawn animation, wanted to ensure Ed, Edd n Eddy was produced in a way similar to cartoons from the 1940s to 1970s.

[4] To give the impression of movement, Ed, Edd n Eddy uses "boiling lines" or shimmering outlines which Antonucci likens to cartoons of the 1930s.

[13] The music of Ed, Edd, n Eddy is heavily influenced by 1930s and 1940s jazz and jump blues, rockabilly, boogie woogie, and the rock and roll of the 1950s.

[23] The six-hour "Ed's Day Off Marathon" aired 22 episodes on January 19, 2004, in celebration of Martin Luther King Jr.

"[25] However, it was quickly followed by "The Eds are Coming" the following month, as part of a special alien-themed event called "Cartoon Network Invaded.

[11][30] The series finale is a movie titled Ed, Edd n Eddy's Big Picture Show, which aired on November 8, 2009.

[36] In 2012, Double D made an appearance in the animated sketch comedy Cartoon Network series Mad episode "Once Upon a Toon.

[43] Ed, Edd n Eddy attracted an audience of 31 million households, was broadcast in 120 countries, and was popular among both children and adults.

David Cornelius of DVD Talk considered the Eds to be child equivalents of The Three Stooges, believing that "the series revels in the sort of frantic, often gross humour kids love so much, and there's just enough oddball insanity at play to make adults giggle just as easily.

"[48] Cornelius also wrote that the "animation is colourful and intentionally bizarre; bold lines forming the characters and backgrounds wiggle and morph in a delirious haze.

Terrence Briggs of Animation World Magazine considered every second of the show "filler" and lamented that the main characters are drawn as "products from the school of acid-trip caricature.

"[53] Bob Higgins, head of creative at Wild Brain, considered Ed, Edd n Eddy to be a "landmark in animation.

"[54] In August 2002, the New York Museum of Television and Radio featured the episode "An Ed Is Born" as part of the special program "Cartoon Power!

[55] The made-for-TV movie Ed, Edd n Eddy's Big Picture Show serves as the series' finale and premiered in the United States on November 8, 2009; although it had completed production a year earlier and first aired in Scandinavia, Australia, and Southeast Asia.

[10][69] The film was directed by Antonucci, who also co-wrote the script with Rachel Connor, Jono Howard, Mike Kubat, and Stacy Warnick.

[28][31][68] The first two seasons of Ed, Edd n Eddy were released on DVD by Warner Home Video in the US and Madman Entertainment in Australia in 2006 and 2007.

The Fools' Par-Ed-Ise DVD, the DVDs of the first two seasons, and several Ed, Edd n Eddy T-shirts were available for purchase on the Cartoon Network Shop.

Amazon Prime added the complete series to its streaming library in December 2022, including the holiday specials and Ed, Edd n Eddy's Big Picture Show.

A short music video was produced with stylized versions of Ed, Edd, Eddy, and Sarah, entitled "The Incredible Shrinking Day" (listed on the Season 2 DVD as "I'm Not Coming in Anymore"),[6] which aired on Cartoon Network in 2002 and 2003.

[91] Ed, Edd n Eddy: The Mis-Edventures was released in 2005 for the GameCube, PlayStation 2, Xbox, Game Boy Advance, and Microsoft Windows.