Edward Mier Mayehoff (July 7, 1909 – November 12, 1992) was an American actor, perhaps best known for his role as Harold Lampson, the henpecked husband and incompetent lawyer in How to Murder Your Wife (1965).

[2] Mayehoff began his career as a musician, playing trombone and leading a dance band in New York hotels.

[6] In the 1954-55 television season, Mayehoff appeared as a construction contractor and former football player trying to impel his son to success on the American football gridiron in That's My Boy, based on the 1951 Dean Martin and Jerry Lewis film of the same name,[5]: 1067  in which Mayehoff played the same part.

Without offering explanation, the Broadway historian Ethan Mordden described Mayehoff as "the most disliked comedian who ever lived who wasn't El Brendel."

Mayehoff's Broadway credits included A Rainy Day in Newark (1963), A Thurber Carnival (1960), A Visit to a Small Planet (1957), Season in the Sun (1950), Concert Varieties (1945), and Rhapsody (1944).