Sclater was born at Hilliers[1] in Petworth into an ancient Sussex family.
Further tragedy befell the family when her nephew was killed at Teheran in October 1918.
[4][5] During the First World War, she operated the Lady Sclater's Work Room and Smokes Fund, was president of the Salisbury branch of the Prisoners of War Packing Association, president of the Soldiers' and Sailors' Families' Association at Central Hackney as well as the Salisbury Plain Pensions Committee.
For these efforts she was appointed a Dame Commander of the Order of the British Empire in the 1918 New Year Honours.
She died on 29 March 1927 of heart failure following pneumonia at her Ovington Gardens home in London.