From 1833 until his death in 1861, he was director of the clinic for gynecology and obstetrics at University of Göttingen, succeeding Caspar Julius Mende.

Von Siebold represented a traditional approach in obstetrics and did not embrace the great medical development at the time.

Inspired by the work of James Young Simpson, Von Siebold introduced the use of ether as a general anaesthetic and was the first to carry out a caesarian section using this substance.

He was succeeded by Jakob Heinrich Hermann Schwartz, who was a student of Gustav Adolf Michaelis and an assistant under Carl Conrad Theodor Litzmann at the University of Kiel.

[1] This article contains content from the Owl Edition of Nordisk familjebok, a Swedish encyclopedia published between 1904 and 1926, now in the public domain.