After completing his university studies, Shalsi practiced teaching in elementary and secondary education in Tirana.

During this period, Shalsi has held important positions, including: Minister of State for Local Affairs and National Coordinator of Anti-Corruption, Chairman of the Standing Parliamentary Committee on Production Activities, Trade and Environment, Deputy Chairman of the Socialist Parliamentary Group, Member of the Delegation of the Assembly of Albania to the EU-Albania Stabilization and Association Committee, Member of the Parliamentary Assembly of the Council of Europe, etc.

Since 2019, he has led the Ministry of State for Protection and Entrepreneurship with great dedication, being every day with businesses in solving their problems.

In 2019, Shalsi was certified by the Harvard Business School in Leading Economic Growth and for more than two years has been a Member of the Ethical Governance Board of Standards of Excellence, Quality Leadership Committee, Vice Chairman of the Global Startup Committee at the World Business Angels Forum (WBAF) as well as Member of the G20 Global Partnership for Financial Inclusion.

Shalsi has been the President of the Albanian Chess Federation since 2016 and is passionate about sports and the musical instrument mandolin.