A member of the Generation of 38, Eduardo Anguita started his literary career during a period marked by Surrealism and Creationism, a movement headed by Vicente Huidobro, to whom he became a close friend.
Alongside Volodia Teitelboim, Anguita published in 1935 the Antología de Poesía Chilena Nueva, which included poems by Vicente Huidobro, Rosamel del Valle, Pablo de Rokha, Pablo Neruda, Humberto Díaz Casanueva, Omar Cáceres, Angel Cruchaga Santa María, Juvencio Valle and both Anguita himself and Teitelboim.
Three years later, a short story by Anguita (Las Hormigas Devoran a un Hombre Llamado David) was included in Miguel Serrano's Antología del verdadero cuento en Chile.
During Carlos Ibáñez del Campo's government (1955), he was named cultural attache in Mexico, where he published Palabras al oído de México in 1960.
These include the pagan idea of an animated reality and the repeal of "myself" from Buddhism, as well as ideals from profane poets connected with the appraisal of the body and eroticism.