[4] He has been a longtime collaborator with many scientists, including his colleague at Stanford University Keith Hodgson for the study of metalloenzyme active sites by x-ray spectroscopy, along with the synthetic chemists Richard H. Holm, Stephen J. Lippard, Lawrence Que Jr. and Kenneth D. Karlin.
In his junior year of high school, he became involved in a local program that allowed exceptional students to work with university professors.
Solomon conducted research with a professor at the University of Miami, using biochemistry and chromatography to study indoles, which led to him becoming Florida's first-ever finalist for the Westinghouse Science Talent Search in 1964.
Solomon spent a year in Copenhagen, Denmark at the Hans Christian Ørsted Institute to work as a postdoctoral fellow under Prof. Carl J.
[2] Solomon began his independent career in late 1975 at the Massachusetts Institute of Technology as an assistant professor, where he continued to study blue copper proteins.