[3] He studied at Yale College, 1859–1863, graduating with a master's degree, and briefly served as his father's aide-de-camp as a captain in the United States Army.

[4] After graduating from Medical College of the New York University, he entered into practice with one of his teachers, William Holme Van Buren.

In 1870 he himself began lecturing on dermatology and genitourinary surgery at Bellevue Hospital Medical College.

[citation needed] Their son, Edward Loughborough Keyes, was like his father a noted urologist.

[citation needed] Edward Lawrence Keyes died from pneumonia at his home in New York on January 24, 1924.