William Holme Van Buren (born in Philadelphia, 5 April 1819; died in New York City, 25 March 1883) was an American surgeon.
Before graduation he left to take his medical education at the University of Pennsylvania, finishing his studies before the legal age at which a diploma could be awarded him.
He attempted to reorganize the university medical school after the fire, insisting on the erection of a building near Bellevue Hospital Center.
This latter work was furnished by the United States Government to the army surgeons during the Civil War.
President Abraham Lincoln offered to make Van Buren Surgeon General at the time of the war, and on his refusal consulted him with regard to the appointment.