Edward Ray Weidlein (July 14, 1887 – August 15, 1983) was an American chemist and later director, chairman, and president at the Mellon Institute of Industrial Research in Pittsburgh.

[4] He spent four years as a Mellon fellow on metallurgical research in Arizona and Nevada.

[1] In November 1916, Weidlein moved to Pittsburgh to work as assistant director of the Mellon Institute of Industrial Research in Oakland.

He became director of the institute in 1921 and served until his appointment as president and chairman of the board of trustees in 1951.

[6][7] During World War II, he helped develop the American synthetic rubber production program.

[2][11] In 1966, he received the AIChE Founders Award for Outstanding Contributions to the Field of Chemical Engineering.