He became 4th Baron Stafford on the death of his father in 1603.
[2] Isabel was reported to be a family chambermaid in a letter to the Earl of Leicester which includes "My Lorde Stafford's son is basely married to his mother's chambermaid.
"[3] Edward Stafford continued on with his father's patronage of the Lord Stafford's Company, a travelling group of players, who were active until at least 1617.
[4] Stafford had one son, Edward (1602 – 6 April 1621).
This son married Ann Wilford, daughter of James Wilford, Newman Hall, Quendon, Essex, and had two children: