[1] Alongside Adrien Raet,[2] she is one of two pupils known to have studied under the illuminator Willem Vrelant.
[3] Vrelant taught manuscript illustration and book production in Bruges, and archives of the studio list Scepens as one of his students in 1476.
Together with Scepens, Madame Vrelant ran the prolific studio, which produced portrait miniatures, calligraphy and capital letter decoration for manuscripts.
[1] In 1476, Scepens gained membership in the St. John the Evangelist Guild for scribes, illuminators and bookbinders.
[5] Scepens was part of the Northern Renaissance, and along with Margaret van Eyck, is one of the few known 15th-century Flemish women artists.