She possessed a limpid, flexible, and resonant voice with an exceptionally wide range, and according to Stendhal was a consummate and enchanting comic actress.

That spring she sang in four comic operas there: revivals of Mayr's Che Originali!, Gazzaniga's Fedeltà ed amore alla prova, and Portugal's Le Donne cambiate, and the premiere of Orlandi's Il Podestà di Chioggia.

Never again shall there be born into the world, solely for the purpose of ministering to the frivolous pleasures of sophisticated people, another living being that so shone and sparkled, whose wit was more irrepressible, nor whose merriment was more irresistible.

She performed in numerous operas at the Theatro de São Carlos between 1803 and 1805, including the world premiere of Fioravanti's La donna soldato.

The young women in the São Carlos audiences were fascinated by her way of styling her thick blond hair to look artfully "dishevelled" and soon began imitating it.

Gafforini starred in the premiere of Benedetto Neri's [it] I saccenti alla moda (The Fashionable Prigs), a dramma giocoso satirizing the political regime of Milan.

Although the repertoire throughout her main career had been overwhelmingly in the opera buffa genre where she excelled, she had sung similar roles in her early days in Venice: Giulio Cesare (Julius Caesar) in Francesco Bianchi's La morte di Cesare and Giovanni Talbot (John Talbot) in Gaetano Andreozzi's Giovanna d'Arco, both at La Fenice in 1797.

She appeared there in Orlandi's La dama soldato, Portugal's Oro non compra amore, and Mosca's Il salto di Leucade.

On her return to Milan, Gafforini and her lover, Antonio Gasparinetti, were married at the Chiesa di San Fedele on 1 April 1812.

Their daughter and only child, Eugenia, was born later that year some time after Gafforini's summer appearance at the Teatro Eretenio in Vicenza in La dama soldato.

[9][2][13] In 1815 Gafforini sang once again at La Scala in Il mistico omaggio, a cantata by Vincenzo Federici and Ferdinando Orlandi sung in the presence of Archduke John of Austria to mark the return of Milan to Austrian control.