[4] During her time as Information and Privacy Commissioner for British Columbia, Denham called for the proactive disclosure of records[5] and published best practices for government ministries and public bodies.

In May 2017, Denham decided to look into potential unlawful marketing involving repurposing of data during the 2016 United Kingdom European Union membership referendum.

[7] When Denham produced her final report in November 2020, she announced that she had "found no further evidence to change [her] earlier view that SCL Group and Cambridge Analytica were not involved in the EU referendum campaign in the UK.

[15] Denham has also authored or co-authored a spate of opinions and articles in 2022: including the essay “Citizens first” for the academic journal Information Polity;[16] a call for increasing collaboration among Canada’s digital regulators, posted to the C. D. Howe Institute’s website;[17] and an opinion in Canada's Globe and Mail newspaper that argued for coordinated, global efforts to create harmonized, comprehensive legal protections for children’s online safety.

[23] In 2020 she was announced as the winner of BCS, The Chartered Institute for IT’s Society Medal as a result of her office's investigation into unlawful data collection practices by political campaigns.

[25][26] Denham received an honorary doctorate of laws in 2022 from the University of Victoria, in British Columbia, for recognition of her international contributions to privacy and access over decades.