She was the daughter of Queen Elizabeth's Lord Keeper of the Great Seal, Sir Nicholas Bacon, by his first wife, Jane Ferneley (d. 1552).

Born about 1541, she was the eldest daughter of Sir Nicholas Bacon, Queen Elizabeth's Lord Keeper of the Great Seal, by his first wife, Jane Ferneley (d.1552).

[6] While serving as a Justice of the Peace at the Oxford assizes of 4–7 July 1577, Doyley and others were, according to John Stowe,[7] infected with a 'strange sickness', whereof the jurors, including 'Sir Robert de Olie', died.

However, over time her link to the book was forgotten, and it was firmly established only recently by John Harley,[9] following earlier suggestions by Thurston Dart[10] and Alan Brown.

According to Harley, in a letter to his brother-in-law, Sir Nathaniel Bacon, in early 1590 Neville referred to his third wife as 'Betty', and stated that she wore 'the bryches' in the household.

[12] Before the end of September 1595, Elizabeth Bacon married, as her third husband and as his third wife, Sir William Peryam, Chief Baron of the Exchequer.

[18] Elizabeth Bacon married firstly, Sir Robert D'Oylie (d. July 1577) of Chislehampton, Oxfordshire, and Greenlands in Hambleden, Buckinghamshire.

[21][22] In the will of their grandmother, Frances (née Thwaytes) Gresham, dated 20 October 1580 and proved 9 November 1580, Neville's children by his second marriage are named as Henry, Edward, Francis, William, and Katherine.