At the end of the first World War, she went to work in Washington D.C., with the American Red Cross as a historian and publicist until eventually making propaganda shorts for the non-profit organization.

[6] In her earlier career, Elizabeth Pickett was a silent short-film director and a screenwriter who wrote scenarios and titles for Fox Film Corporation.

[4] Pickett helped to write and direct nearly forty "short series" films for Fox until eventually becoming the West Coast supervisor.

Pickett wrote several original stories such as Navajo and Wolf Fangs and adapted and titled works including Wings of the Storm, and The Monkey Talks.

Other contributions she made in the film industry include titling and editing Kentucky Pride, Exploring the Amazon, Whispering Sage, The Shamrock Handicap, and Marriage License?

[5] Before beginning to write the screenplay for Redskin Pickett spent months with Native Americans gathering information about their characteristics and behavior in order to gain better insight on their culture for the movie.

According to her UPI obituary, she served on the Board of Governors of the American Red Cross in 1952, and President-elect John F. Kennedy considered her for the post of United States Secretary of the Treasury in 1960 or 1961.