[2] While their marital problems continued they were associated together in the last years of Henry's reign, signing documents and jointly petitioning the crown regarding property.

Thomas never got the barony he wanted, through marriage or his own merits, and the last was not heard regarding his and his wife's problems; on 13 June 1550 the Privy Council meeting was called up to intervene in a "Domestic Quarrel", the details of which are unknown.

In early 1553, Elizabeth married for the second time, to Ambrose Dudley, a younger son of the Duke of Northumberland, then Lord President of the Council and de facto regent for King Edward VI.

After Edward's death and Northumberland's attempt to place his daughter-in-law Lady Jane Grey on the throne, Ambrose was imprisoned with his father and brothers.

In late 1554, Elizabeth commissioned Roger Ascham to write a Latin petition to Queen Mary I and her husband Philip of Spain, seeking pardon for Ambrose.