Ellen Maria Wade Colfax (July 26, 1836 – March 4, 1911) was the second wife of Schuyler Colfax, who became the first House speaker to be elected vice president when he ran on a ticket headed by Ulysses S. Grant in 1868.

[1] On November 18, 1868, just two weeks after the 1868 presidential election, Ellen Maria Wade married the man who had defeated her uncle, Senator Benjamin Franklin Wade of Ohio, in the race for the Republican vice presidential nomination.

Likewise, Ellen Maria Colfax became the second lady of the United States.

She died at her home in South Bend, Indiana in 1911 after a period of poor health, on the 42nd anniversary of her husband's assumption of the vice-presidency.

[4][5] Her funeral was held March 7, 1911, at the Colfax home, and she was buried next to her husband at South Bend City Cemetery.