Mariette Elizabeth "Ettie" Rheiner Garner (July 17, 1869 – August 17, 1948) was the wife of John Nance Garner, the 32nd vice president of the United States, and thus second lady of the United States from 1933 to 1941.

[1] Mariette Elizabeth "Ettie" Rheiner Garner was born in Sabinal, Texas in 1869, to John Peter Rheiner, a Swiss immigrant who became a Texas rancher, and his first wife, the former Mary Elizabeth Watson.

[2][3] In 1893, although women in Texas could not vote at the time, Mariette Rheiner ran for Uvalde County judge.

[2] During her husband's tenure in the U.S. House of Representatives, from 1903 to 1933, Ettie Garner served as his private secretary.,[2] prior to her role as second lady of the United States.

She suffered from Parkinson's disease from 1942 to 1948, slipped into a two-day coma and died in Uvalde, Texas, on August 17, 1948, a month after her 79th birthday.