[16][17] Roche returned to NUIG as a post-doctoral research fellow under Peter McHugh, where she used computational methods (finite element analysis) to analyze drug release kinetics from implantable devices.
[27] Roche also developed a device named 'Therepi' that attaches directly to a damaged heart and acts as a reservoir for drugs or cells that can be refilled multiple times from a port under the skin.
[29] The device's reservoir can be implanted on the heart in a single surgical procedure, minimizing the amount of surgeries required.
[30][31][32] In 2019, Roche was a named author on the invention of a dry double-sided tape that can be used for the adhesion of wet tissue and devices.
[37] In 2018, Roche gave the Keynote Speech at Impact,[38] a technology conference in Krakow, where she discussed soft robotics.