[1] Spertus has written articles treating both technical and social subjects, often combining the two.

In 1993, she was profiled in The New York Times as one of the "women who might change the face of the computer industry" and in a follow-up article in 2003.

[5][6] While at Google,[2] Spertus spent her time working on App Inventor for Android, a block based development platform with a graphical user interface (GUI) that lets developers and amateurs create applications for Android.

[7] In May 2011, O'Reilly Media published the book App Inventor, which Spertus co-authored with David Wolber, Hal Abelson, and Liz Looney.

[4] In 2014, she went on Sabbatical from Mills to work with Google for the development of the Blockly programming environment.