Nohejlová-Prátová was born on 3 June 1900 in Opatovice nad Labem, east Bohemia, then part of Austria-Hungary.

[2] In 1918 Nohejlová-Prátová caught influenza as a result of the pandemic of Spanish flu that swept Europe, and this illness delayed her graduation.

[2] Nevertheless, she graduated from high school and went on the study History at the Faculty of Arts, Charles University, Prague; one of her tutors was the Czech historian, Professor J. V.

During her time at University, she became engaged, however in 1923 her fiancee died as a result of injuries received during World War I.

Nohejlová-Prátová was arrested by the Gestapo on 4 February 1942, she was interrogated at Petschek Palace and imprisoned because she had used crystals from the mineralogy department to build radios, which supplied news at odds with Nazi propaganda.

[6] In Nohejlová-Prátová's work on Czech coinage in the tenth and eleventh century, she believed that numismatics tended to over-estimate the link between iconography and contemporary politics.