[3] His companions are his best friends: Sam Manson, a vegetarian goth girl who is entranced by the "weird and supernatural" and Tucker Foley, a lighthearted "techno-geek".

He is initially shown as an average, self-conscious, introverted, kindhearted, and sensitive[5][6] 14-year-old boy who is desperate to fit in with his peers and be accepted, despite his parents' eccentricities.

[1] Her parents are well-to-do social conservatives who inherited money from their famous inventor ancestor, who invented "the machine that twirls the cellophane around the toothpicks", though she briefly kept this a secret from her friends to avoid "fake friendships".

Viewing herself as the most rational and normal member of the family, Jazz often plays a surrogate parental role to Danny, thinking he's a naive child in need of guidance,[13][22] unaware that she is often smothering him.

Due to her cherished goal of being a psychologist, Jazz has a bad habit of getting into people's personal space,[23] which greatly annoys her brother, despite his knowing that she does it because she loves him and wants nothing more than to help him.

[9] While he can often act clumsy and incompetent, he holds a great deal of courage and is an adequate fighter,[3] at one point clashing toe-and-toe against Vlad Plasmius and defeating him, much to the latter's surprise and embarrassment.

He is a self-proclaimed scientist[24] who has a good amount of technical knowledge, and is able to conjure up ghost gadgets and defense systems built all around the Fenton household.

2 of the "Danny Phantom Ten Years Later" video on YouTube, Butch Hartman admits he partially based Jack off Fred Flintstone.

[30] Maddie (short for Madeline)[8] is an accomplished ninth-degree martial artist[3] who serves as Jack's partner and equal inventor of Fenton anti-ghost gadgets.

Constituting a parody of the comics-character Chameleon, Amorpho (voiced by Danny Mann) is a ghost able to change his appearance into that of any (human or animal) being, at will.

More mischievous than malevolent, he desires attention and pursues it by morphing into someone else's appearance, to play pranks that leave the corresponding person to take the consequences, for what he actually had done.

[10] The Box Ghost (voiced by Rob Paulsen) is a running gag ghoul who constantly fights with cardboard and anything square[32] (and the occasional bubble wrap).

[35] He was almost successful in taking over Amity Park by using Pandora's Box, but failed (in that episode, he was summed-up as 'a ghost with an inferiority complex, who just wants attention').

[17] After returning from beyond the grave as a genie/wishing ghost, Desiree initially granted wishes with benevolence, but remembering her own happiness that was taken away, she became bitter, resentful, and jealous, thus leading to her current behavior.

[28] Hotep-Ra (voiced by S. Scott Bullock) is the mummy-like spirit of an ancient minion of King Duulamun, an Egyptian pharaoh who shares a remarkably similar appearance to Tucker Foley.

[32] He uses raw power and weaponry, but understands the way of the hunt, so he is able to utilize his brain to take advantage of his situation as predator to one-up his prey.

One running gag in the show is that since he has Tucker's PDA in his armor, while he has more power, he gets interrupted a few times into doing research on the purple back gorilla, much to his frustration.

To do so, she often targets teenagers and through elaborate plans, slowly sucks them dry of their positive emotions like a kind of psychic vampire, using their worst fears and anxieties to humiliate and drain them, leaving them depressed and apathetic while she absorbs their energy to continuously strengthen and beautify her form.

[35] In his upgraded 2.0 form, Technus doesn't shout out his secret plans as often, he is larger, taller and more powerful, sporting a black trench coat and long silver cape.

A rich, debonair billionaire, Vlad is a powerful half-ghost businessman and scientist whose twenty years of experience constantly one-up Danny's ghostly abilities.

As the main antagonist in the series, he vows to destroy Jack for giving him his ghost powers, which in the process injured him terribly and put him in the hospital for seven years with a fatal condition known as "Ecto Acne".

At the end of the series he reveals his ghost side in an attempt to secure world domination, but fails and is left as a wandering space nomad.

His ghost surname, "Plasmius" is devised from "plasma" which doubly can be a reference to "blood" or ectoplasm - underlining both the former vampire element and the current 'ghost' connection.

[54] Vortex (voiced by Dave Boat) is a psychotic ghost with the power to control the weather, a gift he considers to be an art form.

Vortex can generate and control storms, and the weather in general, from creating typhoons to making heat waves hot enough to melt walls, floods and winds cold enough to freeze streets in ice.

[29] Colloquially referred to as The Guys in White (spoofing the Men In Black), they are usually represented by Operatives K and O, who are tasked with capturing Danny Phantom.

Voiced by Colleen O'Shaughnessey, Dee Bradley Baker, and Rob Paulsen Vid, Thrash, and Download are a trio of teen ghost hunters, created by Vlad to shame Danny and dethrone him as resident savior of Amity Park.

Once a popular shallow girl, Valerie's life takes a turn for the worse when accidents caused by Cujo the ghost dog cost her father his job.

[4] Clockwork (voiced by David Carradine in the TV series and Piotr Michael in Nickelodeon All-Star Brawl 2) is a ghost who controls and keeps the flow of time.

When she first emerged from the Ghost Zone, her despair over not being allowed to go the Princess ball by her mother caused her to turn into a dragon and fight Danny.