Emil "Tom" Frei III (February 21, 1924 – April 30, 2013) was an American physician and oncologist.

Anderson he was the founding director of the Department of Development Therapeutics, which evolved into the Clinical Research Center.

[4] His groundbreaking research into then-controversial combination chemotherapy, including the VAMP regimen, earned him many awards.

[7] In 1972 he received the Lasker-DeBakey Clinical Medical Research Award from the Lasker Foundation "for his outstanding contribution in application of the concept of combination chemotherapy for lymphoma and acute adult leukemia.

[9] Frei died of Parkinson's disease at his home in Oak Park, Illinois on April 30, 2013.