[2] At age nineteen, Mikue Ondo made her official debut for the 2004 Summer Olympics in Athens, where she competed in the women's 800 metres.

She finished seventh in the fourth heat of the event by sixteen seconds behind Kenya's Faith Macharia, with her slowest possible time of 2:22.88.

At the 2008 Summer Olympics in Beijing, Mikue Ondo competed again for the second time in the women's 800 metres.

Mikue Ondo, however, failed to advance into the semi-finals, as she placed thirty-ninth overall, and was ranked farther below three mandatory slots for the next round.

She was eventually upgraded to a higher overall position when Croatia's Vanja Perišić had been disqualified for failing the doping test.