His half-brother was the politician Christopher Julius Høgh-Guldberg and his grandfather was Ove Høegh-Guldberg.

He studied painting under Christian August Lorentzen and later graduated from the plaster school in July 1828.

While working at the Cathedral School he was also principal of Prins Frederik Ferdinands Tegneskole, which would later become Aarhus Tech.

Christian Gebauer was Høegh-Guldbergs teacher and mentor while he studied at the Academy of Fine Arts in Copenhagen.

[1][2] Bjørnejagt (by sketch of Gebauer, 1833, National Gallery of Denmark); En brølende tyr (exh.