The Enistustikweyach River is a tributary of Dana Lake (Eeyou Istchee Baie-James) in Regional County Municipality (RCM) of Eeyou Istchee James Bay (municipality), in the administrative region of Nord-du-Québec, in the Canadian province of Quebec, in Canada.

The surface of the river is usually frozen from early November to mid-May, however, safe circulation on ice is generally from mid-November to mid-April.

The main neighboring hydrographic slopes are: The Enistustikweyach River originates at the mouth of a small unidentified lake (elevation: 253 metres (830 ft)) surrounded by marsh and located at: From the mouth of Enistustikweyach Lake, the Enistustikweyach River flows on 39.1 kilometres (24.3 mi) according to the following segments: The "Enistustikweyach River" flows into the Southwest Bay bottoms on the southwestern shore of Evans Lake which is crossed by the Broadback River.

This confluence is located at: Of Cree origin, the term "Enistustikweyach" means "the river where three streams converge".

The toponym "Enistustikweyach River" was formalized on October 5, 1982 at the Commission de toponymie du Québec[3] Download coordinates as: