Enoch Lewis (born in Radnor Township, Delaware County, Pennsylvania 29 January 1776; died in Philadelphia, 14 June 1856) was a mathematician.

He early exhibited a talent for mathematics, at the age of fourteen was usher in a country school, and at fifteen became principal.

In the autumn of 1792 he removed to Philadelphia, studied mathematics, teaching half of each day to earn his support, and in 1795 was engaged as a surveyor in laying out towns in western Pennsylvania under the direction of Andrew Ellicott.

Zitarelli writes We describe six of its major contributors, two of whom are known somewhat (Robert Adrain and Robert M. Patterson), but the other four seem to have slipped into obscurity in spite of accomplishments that deserve more recognition (William Lenhart, Enoch Lewis, John Gummere, and John Eberle).

He published an advanced textbook on spherical projections expanding the Appendix in Simpson's Trigonometry book.